Phenyl b-D-thioglucopyranoside

苯基-β-D-硫代葡萄糖苷,

(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-3,4,5-triol is a chemical compound that has gained attention in the field of scientific research due to its potential applications in various industries. This paper aims to provide a comprehensive overview of the background, physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions of (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-3,4,5-triol.

Definition and Background:

(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-3,4,5-triol, also known as PTT or thio-PTT, is a tetrahydroxytetrahydropyran compound that is structurally similar to the natural sugar, D-glucose. The incorporation of a thiol group (–SH) into the phenyl ring of PTT increases its reactivity towards metal ions and proteins, making it useful in various biological and chemical applications.

Synthesis and Characterization:

PTT can be synthesized through a variety of methods, including the acid-catalyzed reaction of D-mannitol and thiophenol, the modified Wittig reaction, and the Michael addition reaction. The characterization of PTT can be achieved through various analytical techniques, including NMR spectroscopy, IR spectroscopy, and X-ray diffraction analysis.

Analytical Methods:

The analysis of PTT can be achieved through various analytical techniques, including chromatographic techniques (HPLC), spectrophotometric techniques (UV-Visible Spectroscopy), and mass spectrometry (MS).

Biological Properties:

PTT has been shown to exhibit anti-inflammatory, antioxidant, and antidiabetic activities in vitro and in vivo. It has also been shown to possess antitumor activity and has been studied for its potential as an anticancer drug.

Toxicity and Safety in Scientific Experiments:

Studies have shown that PTT is relatively non-toxic and exhibits low acute toxicity in animals. However, further studies are required to assess its long-term toxicity and safety in humans.

Applications in Scientific Experiments:

PTT has been used in various scientific experiments, including metal ion detection, protein modification, and drug delivery. It has also been studied for its potential use in the development of new materials, such as hydrogels and nanocomposites.

Current State of Research:

Research on PTT is still in its early stages, with most studies focusing on its biological activities and potential applications in drug delivery and materials science.

Potential Implications in Various Fields of Research and Industry:

PTT has significant potential in various fields of research and industry, including drug delivery, biomedical engineering, and materials science. It may also have applications in agriculture, food science, and environmental engineering.

Limitations and Future Directions:

Despite its promising properties, the use of PTT in various applications is limited by its high cost, low solubility, and poor stability. Future research should focus on developing more efficient synthetic methods, improving its stability and solubility, and exploring its potential applications in various fields.

Future Directions:

1. Development of more efficient synthetic methods for PTT.

2. Improving the stability and solubility of PTT.

3. Studying the potential applications of PTT in agriculture and food science.

4. Investigating the potential environmental implications of PTT.

5. Studying the interactions of PTT with cells and tissues in vivo.

6. Developing new materials based on PTT.

7. Studying the potential applications of PTT in energy storage.

8. Exploring the potential of PTT as a theranostic agent.

9. Developing new analytical techniques for the detection and quantification of PTT.

10. Investigating the potential of PTT in tissue engineering.